Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50337342'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50337342 (2-(2,6-difluorophenyl)-1-(4-(4-(5-methyl-1H-pyrazo...) Show SMILES Cc1cc(Nc2nc(nn3cccc23)N2CCN(CC2)C(=O)Cc2ccc(F)cc2F)[nH]n1 Show InChI InChI=1S/C22H22F2N8O/c1-14-11-19(28-27-14)25-21-18-3-2-6-32(18)29-22(26-21)31-9-7-30(8-10-31)20(33)12-15-4-5-16(23)13-17(15)24/h2-6,11,13H,7-10,12H2,1H3,(H2,25,26,27,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of JAK2 after 60 mins				Bioorg Med Chem Lett 21: 1425-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.022 BindingDB Entry DOI: 10.7270/Q2MG7PRT
					More data for this Ligand-Target Pair