Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50439012'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439012 (CHEMBL2420812) Show SMILES CCNC(=O)Nc1cc(NC(=O)c2c(Cl)cccc2Cl)ccn1 Show InChI InChI=1S/C15H14Cl2N4O2/c1-2-18-15(23)21-12-8-9(6-7-19-12)20-14(22)13-10(16)4-3-5-11(13)17/h3-8H,2H2,1H3,(H3,18,19,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair