Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50446993'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50446993 (CHEMBL3116052) Show SMILES C[C@H](Nc1nc(Nc2cn(C)cn2)c2ccn(C3CC3)c2n1)c1ncc(F)cn1 |r| Show InChI InChI=1S/C19H20FN9/c1-11(16-21-7-12(20)8-22-16)24-19-26-17(25-15-9-28(2)10-23-15)14-5-6-29(13-3-4-13)18(14)27-19/h5-11,13H,3-4H2,1-2H3,(H2,24,25,26,27)/t11-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of Jak2 (unknown origin)				J Med Chem 57: 144-58 (2014) Article DOI: 10.1021/jm401546n BindingDB Entry DOI: 10.7270/Q2CR5VTM
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