Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM316821'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM316821 (2-[(1-acryloyl-4-methylpiperidin-4-yl)amino]-N-(pr...) Show SMILES CC(C)NC(=O)c1c[nH]c2ncc(NC3(C)CCN(CC3)C(=O)C=C)nc12 Show InChI InChI=1S/C19H26N6O2/c1-5-15(26)25-8-6-19(4,7-9-25)24-14-11-21-17-16(23-14)13(10-20-17)18(27)22-12(2)3/h5,10-12H,1,6-9H2,2-4H3,(H,20,21)(H,22,27)(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description JAK Caliper Enzyme Assay at 4 μM: Test article was solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 30 mM. An 11-point half ...				Citation and Details BindingDB Entry DOI: 10.7270/Q29026XR
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM316821 (2-[(1-acryloyl-4-methylpiperidin-4-yl)amino]-N-(pr...) Show SMILES CC(C)NC(=O)c1c[nH]c2ncc(NC3(C)CCN(CC3)C(=O)C=C)nc12 Show InChI InChI=1S/C19H26N6O2/c1-5-15(26)25-8-6-19(4,7-9-25)24-14-11-21-17-16(23-14)13(10-20-17)18(27)22-12(2)3/h5,10-12H,1,6-9H2,2-4H3,(H,20,21)(H,22,27)(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description Test article was solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 30 mM. An 11-point half log dilution series was created in DMSO...				US Patent US9617258 (2017) BindingDB Entry DOI: 10.7270/Q2JD4ZWG
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM316821 (2-[(1-acryloyl-4-methylpiperidin-4-yl)amino]-N-(pr...) Show SMILES CC(C)NC(=O)c1c[nH]c2ncc(NC3(C)CCN(CC3)C(=O)C=C)nc12 Show InChI InChI=1S/C19H26N6O2/c1-5-15(26)25-8-6-19(4,7-9-25)24-14-11-21-17-16(23-14)13(10-20-17)18(27)22-12(2)3/h5,10-12H,1,6-9H2,2-4H3,(H,20,21)(H,22,27)(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21.3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description JAK Caliper Enzyme Assay at 1 mM ATP: Test article was solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 30 mM. An 11-point half l...				Citation and Details BindingDB Entry DOI: 10.7270/Q29026XR
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM316821 (2-[(1-acryloyl-4-methylpiperidin-4-yl)amino]-N-(pr...) Show SMILES CC(C)NC(=O)c1c[nH]c2ncc(NC3(C)CCN(CC3)C(=O)C=C)nc12 Show InChI InChI=1S/C19H26N6O2/c1-5-15(26)25-8-6-19(4,7-9-25)24-14-11-21-17-16(23-14)13(10-20-17)18(27)22-12(2)3/h5,10-12H,1,6-9H2,2-4H3,(H,20,21)(H,22,27)(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21.3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description Test article was solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 30 mM. An 11-point half log dilution series was created in DMSO...				US Patent US9617258 (2017) BindingDB Entry DOI: 10.7270/Q2JD4ZWG
					More data for this Ligand-Target Pair