Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50109513'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50109513 (CHEMBL3601717) Show SMILES COc1cc(ccc1Nc1ncc(C#N)c(NCc2cccc(NC(=O)C=C)c2)n1)N1CCN(C)CC1 Show InChI InChI=1S/C27H30N8O2/c1-4-25(36)31-21-7-5-6-19(14-21)17-29-26-20(16-28)18-30-27(33-26)32-23-9-8-22(15-24(23)37-3)35-12-10-34(2)11-13-35/h4-9,14-15,18H,1,10-13,17H2,2-3H3,(H,31,36)(H2,29,30,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by Z'-Lyte assay				J Med Chem 58: 6589-606 (2015) Article DOI: 10.1021/acs.jmedchem.5b00710 BindingDB Entry DOI: 10.7270/Q2833TSH
					More data for this Ligand-Target Pair