Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM13217'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13217 (2-[[(tert-Butyloxy)carbonyl]-amino]-4-methyl-N-(2,...) Show SMILES Cc1nc(NC(=O)OC(C)(C)C)sc1C(=O)Nc1c(C)cc(C)cc1C Show InChI InChI=1S/C19H25N3O3S/c1-10-8-11(2)14(12(3)9-10)21-16(23)15-13(4)20-17(26-15)22-18(24)25-19(5,6)7/h8-9H,1-7H3,(H,21,23)(H,20,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13217 (2-[[(tert-Butyloxy)carbonyl]-amino]-4-methyl-N-(2,...) Show SMILES Cc1nc(NC(=O)OC(C)(C)C)sc1C(=O)Nc1c(C)cc(C)cc1C Show InChI InChI=1S/C19H25N3O3S/c1-10-8-11(2)14(12(3)9-10)21-16(23)15-13(4)20-17(26-15)22-18(24)25-19(5,6)7/h8-9H,1-7H3,(H,21,23)(H,20,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human p56 Lck tyrosine kinase				Bioorg Med Chem Lett 13: 4007-10 (2003) BindingDB Entry DOI: 10.7270/Q2CC103J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13217 (2-[[(tert-Butyloxy)carbonyl]-amino]-4-methyl-N-(2,...) Show SMILES Cc1nc(NC(=O)OC(C)(C)C)sc1C(=O)Nc1c(C)cc(C)cc1C Show InChI InChI=1S/C19H25N3O3S/c1-10-8-11(2)14(12(3)9-10)21-16(23)15-13(4)20-17(26-15)22-18(24)25-19(5,6)7/h8-9H,1-7H3,(H,21,23)(H,20,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of phosphorylation ofan exogenous substrate by human p56 Lck tyrosine kinase expressed as a Histagged protein in insect cells usi...				Bioorg Med Chem Lett 13: 2145-9 (2003) BindingDB Entry DOI: 10.7270/Q2F76BZ1
					More data for this Ligand-Target Pair