Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM13221'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13221 (BMS-354825 tert-Butoxycarbamate Analog 5e | CHEMBL...) Show SMILES Cc1nc(NC(=O)OC(C)(C)C)sc1C(=O)Nc1c(Cl)cccc1Cl Show InChI InChI=1S/C16H17Cl2N3O3S/c1-8-12(13(22)20-11-9(17)6-5-7-10(11)18)25-14(19-8)21-15(23)24-16(2,3)4/h5-7H,1-4H3,(H,20,22)(H,19,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Lck(hLck) kinase				Bioorg Med Chem Lett 13: 4007-10 (2003) BindingDB Entry DOI: 10.7270/Q2CC103J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13221 (BMS-354825 tert-Butoxycarbamate Analog 5e | CHEMBL...) Show SMILES Cc1nc(NC(=O)OC(C)(C)C)sc1C(=O)Nc1c(Cl)cccc1Cl Show InChI InChI=1S/C16H17Cl2N3O3S/c1-8-12(13(22)20-11-9(17)6-5-7-10(11)18)25-14(19-8)21-15(23)24-16(2,3)4/h5-7H,1-4H3,(H,20,22)(H,19,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair