Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM17731'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM17731 (2,6-dimethylphenyl N-(2-{[4-(4-methylpiperazin-1-y...) Show SMILES CN1CCN(CC1)c1ccc(Nc2nccc(n2)N(C(=O)Oc2c(C)cccc2C)c2ccc3ccccc3c2)cc1 Show InChI InChI=1S/C34H34N6O2/c1-24-7-6-8-25(2)32(24)42-34(41)40(30-14-11-26-9-4-5-10-27(26)23-30)31-17-18-35-33(37-31)36-28-12-15-29(16-13-28)39-21-19-38(3)20-22-39/h4-18,23H,19-22H2,1-3H3,(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	7.5	22
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 49: 4981-91 (2006) Article DOI: 10.1021/jm060435i BindingDB Entry DOI: 10.7270/Q2SB440C
					More data for this Ligand-Target Pair