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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM50045936 ((E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol | (E)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of p56 Lck tyrosine kinase | Bioorg Med Chem Lett 8: 2489-94 (1999) BindingDB Entry DOI: 10.7270/Q2D50M3V | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM50045936 ((E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol | (E)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article | n/a | n/a | 6.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration against phosphoylation of angiotensin I catalyzed by protein-tyrosine kinase p56lck | Bioorg Med Chem Lett 1: 215-218 (1991) Article DOI: 10.1016/S0960-894X(00)80255-3 BindingDB Entry DOI: 10.7270/Q2CF9Q0M | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM50045936 ((E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol | (E)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 6.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Tested in vitro for the inhibition of protein-tyrosine kinase p56lck using angiotensin I (1.2 mM) and [gamma-32P]-ATP (50 pM) | J Med Chem 36: 2950-5 (1993) BindingDB Entry DOI: 10.7270/Q23J3C2N | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM50045936 ((E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol | (E)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 8.18E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Technical University of Braunschweig Curated by ChEMBL | Assay Description Inhibition of tyrosine kinase p56-lck | J Nat Prod 62: 927-30 (1999) Article DOI: 10.1021/np990010h BindingDB Entry DOI: 10.7270/Q2FR00DM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM50045936 ((E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol | (E)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 8.18E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of p56 lck | J Nat Prod 55: 1529-1560 (1992) Article DOI: 10.1021/np50089a001 BindingDB Entry DOI: 10.7270/Q2J966CC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM50045936 ((E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol | (E)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 8.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University Curated by ChEMBL | Assay Description Inhibition of LCK | J Nat Prod 69: 14-7 (2006) Article DOI: 10.1021/np050229y BindingDB Entry DOI: 10.7270/Q2FJ2GHF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
