Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50112921'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50112921 (CHEMBL25969 | Imidazo[1,5-a]quinoxalin-4-yl-(2,4,6...) Show SMILES Cc1cc(C)c(Nc2nc3ccccc3n3cncc23)c(C)c1 Show InChI InChI=1S/C19H18N4/c1-12-8-13(2)18(14(3)9-12)22-19-17-10-20-11-23(17)16-7-5-4-6-15(16)21-19/h4-11H,1-3H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against recombinant p56 Lck tyrosine kinase expressed as a His-tagged protein in insect cells using a baculovirus expression syst...				Bioorg Med Chem Lett 12: 1361-4 (2002) BindingDB Entry DOI: 10.7270/Q2R78DJ1
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50112921 (CHEMBL25969 | Imidazo[1,5-a]quinoxalin-4-yl-(2,4,6...) Show SMILES Cc1cc(C)c(Nc2nc3ccccc3n3cncc23)c(C)c1 Show InChI InChI=1S/C19H18N4/c1-12-8-13(2)18(14(3)9-12)22-19-17-10-20-11-23(17)16-7-5-4-6-15(16)21-19/h4-11H,1-3H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
University of Zurich Curated by ChEMBL					Assay Description Inhibition of Lck				J Med Chem 51: 1179-88 (2008) Article DOI: 10.1021/jm070654j BindingDB Entry DOI: 10.7270/Q29Z95RD
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50112921 (CHEMBL25969 | Imidazo[1,5-a]quinoxalin-4-yl-(2,4,6...) Show SMILES Cc1cc(C)c(Nc2nc3ccccc3n3cncc23)c(C)c1 Show InChI InChI=1S/C19H18N4/c1-12-8-13(2)18(14(3)9-12)22-19-17-10-20-11-23(17)16-7-5-4-6-15(16)21-19/h4-11H,1-3H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Evaluated for inhibition of human p56 Lck tyrosine kinase				J Med Chem 47: 2534-49 (2004) Article DOI: 10.1021/jm0304358 BindingDB Entry DOI: 10.7270/Q2KH0P3P
					More data for this Ligand-Target Pair