Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50112931'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50112931 ((2,6-Dichloro-phenyl)-imidazo[1,5-a]quinoxalin-4-y...) Show SMILES Clc1cccc(Cl)c1Nc1nc2ccccc2n2cncc12 Show InChI InChI=1S/C16H10Cl2N4/c17-10-4-3-5-11(18)15(10)21-16-14-8-19-9-22(14)13-7-2-1-6-12(13)20-16/h1-9H,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against recombinant p56 Lck tyrosine kinase expressed as a His-tagged protein in insect cells using a baculovirus expression syst...				Bioorg Med Chem Lett 12: 1361-4 (2002) BindingDB Entry DOI: 10.7270/Q2R78DJ1
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50112931 ((2,6-Dichloro-phenyl)-imidazo[1,5-a]quinoxalin-4-y...) Show SMILES Clc1cccc(Cl)c1Nc1nc2ccccc2n2cncc12 Show InChI InChI=1S/C16H10Cl2N4/c17-10-4-3-5-11(18)15(10)21-16-14-8-19-9-22(14)13-7-2-1-6-12(13)20-16/h1-9H,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
University of Zurich Curated by ChEMBL					Assay Description Inhibition of Lck				J Med Chem 51: 1179-88 (2008) Article DOI: 10.1021/jm070654j BindingDB Entry DOI: 10.7270/Q29Z95RD
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50112931 ((2,6-Dichloro-phenyl)-imidazo[1,5-a]quinoxalin-4-y...) Show SMILES Clc1cccc(Cl)c1Nc1nc2ccccc2n2cncc12 Show InChI InChI=1S/C16H10Cl2N4/c17-10-4-3-5-11(18)15(10)21-16-14-8-19-9-22(14)13-7-2-1-6-12(13)20-16/h1-9H,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Evaluated for inhibition of human p56 Lck tyrosine kinase				J Med Chem 47: 2534-49 (2004) Article DOI: 10.1021/jm0304358 BindingDB Entry DOI: 10.7270/Q2KH0P3P
					More data for this Ligand-Target Pair