Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50116406'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50116406 (6,6-Dimethyl-2-(2,4,6-trichloro-phenylamino)-1,6-d...) Show SMILES CC1(C)C(=O)NC(=O)c2c1ccc1nc(Nc3c(Cl)cc(Cl)cc3Cl)[nH]c21 Show InChI InChI=1S/C18H13Cl3N4O2/c1-18(2)8-3-4-11-14(12(8)15(26)25-16(18)27)24-17(22-11)23-13-9(20)5-7(19)6-10(13)21/h3-6H,1-2H3,(H2,22,23,24)(H,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human p56 Lck tyrosine kinase				J Med Chem 45: 3394-405 (2002) BindingDB Entry DOI: 10.7270/Q2CJ8CTW
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