Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM50120127 (CHEMBL106213 | N*4*-(2-Chloro-6-methyl-phenyl)-N*7...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description 50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme. | Bioorg Med Chem Lett 12: 3153-6 (2002) BindingDB Entry DOI: 10.7270/Q2NC60JR | |||||||||||
More data for this Ligand-Target Pair |