Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50126750'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50126750 (2-(2,6-Dichloro-phenylamino)-1-ethyl-6,7-dimethyl-...) Show SMILES CCn1c(Nc2c(Cl)cccc2Cl)nc2ccc3c(C)c(C)[nH]c(=O)c3c12 Show InChI InChI=1S/C20H18Cl2N4O/c1-4-26-18-15(9-8-12-10(2)11(3)23-19(27)16(12)18)24-20(26)25-17-13(21)6-5-7-14(17)22/h5-9H,4H2,1-3H3,(H,23,27)(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of p56 Lck tyrosine kinase				J Med Chem 46: 1337-49 (2003) Article DOI: 10.1021/jm020446l BindingDB Entry DOI: 10.7270/Q2DN44FW
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