Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50126754'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50126754 (2-(2,6-Dichloro-phenylamino)-7-(1-hydroxy-allyl)-1...) Show SMILES Cc1c([nH]c(=O)c2c3n(C)c(Nc4c(Cl)cccc4Cl)nc3ccc12)C(O)C=C Show InChI InChI=1S/C21H18Cl2N4O2/c1-4-15(28)17-10(2)11-8-9-14-19(16(11)20(29)25-17)27(3)21(24-14)26-18-12(22)6-5-7-13(18)23/h4-9,15,28H,1H2,2-3H3,(H,24,26)(H,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of p56 Lck tyrosine kinase				J Med Chem 46: 1337-49 (2003) Article DOI: 10.1021/jm020446l BindingDB Entry DOI: 10.7270/Q2DN44FW
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