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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50129325'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50129325
PNG
(2-[(2-Hydroxymethyl-cyclopropanecarbonyl)-amino]-b...)
Show SMILES Cc1cccc(Cl)c1NC(=O)c1ccc2nc(NC(=O)C3CC3CO)sc2c1
Show InChI InChI=1S/C20H18ClN3O3S/c1-10-3-2-4-14(21)17(10)23-18(26)11-5-6-15-16(8-11)28-20(22-15)24-19(27)13-7-12(13)9-25/h2-6,8,12-13,25H,7,9H2,1H3,(H,23,26)(H,22,24,27)
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PC cid
PC sid
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Similars
PubMed
n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human Lck protein tyrosine kinase

Bioorg Med Chem Lett 13: 2145-9 (2003)


BindingDB Entry DOI: 10.7270/Q2F76BZ1
More data for this
Ligand-Target Pair