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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50131121'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50131121
PNG
(2-(Pyrazin-2-ylamino)-benzothiazole-6-carboxylic a...)
Show SMILES Cc1cccc(Cl)c1NC(=O)c1ccc2nc(Nc3cnccn3)sc2c1
Show InChI InChI=1S/C19H14ClN5OS/c1-11-3-2-4-13(20)17(11)25-18(26)12-5-6-14-15(9-12)27-19(23-14)24-16-10-21-7-8-22-16/h2-10H,1H3,(H,25,26)(H,22,23,24)
PDB

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PC cid
PC sid
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Similars
PubMed
n/an/a 15n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human p56 Lck tyrosine kinase

Bioorg Med Chem Lett 13: 2587-90 (2003)


BindingDB Entry DOI: 10.7270/Q2FX78V4
More data for this
Ligand-Target Pair