Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50131144'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50131144 (2-(4-Dimethylaminomethyl-pyridin-2-ylamino)-benzot...) Show SMILES CN(C)Cc1ccnc(Nc2nc3ccc(cc3s2)C(=O)Nc2c(C)cccc2Cl)c1 Show InChI InChI=1S/C23H22ClN5OS/c1-14-5-4-6-17(24)21(14)28-22(30)16-7-8-18-19(12-16)31-23(26-18)27-20-11-15(9-10-25-20)13-29(2)3/h4-12H,13H2,1-3H3,(H,28,30)(H,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human p56 Lck tyrosine kinase				Bioorg Med Chem Lett 13: 2587-90 (2003) BindingDB Entry DOI: 10.7270/Q2FX78V4
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