Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50194682'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50194682 (CHEMBL213478 | N-methyl-6-(2-methyl-5-(5-(trifluor...) Show SMILES CNc1ncc2cc(ccc2n1)-c1cc(Nc2nc3ccc(cc3[nH]2)C(F)(F)F)ccc1C Show InChI InChI=1S/C24H19F3N6/c1-13-3-6-17(30-23-32-20-8-5-16(24(25,26)27)10-21(20)33-23)11-18(13)14-4-7-19-15(9-14)12-29-22(28-2)31-19/h3-12H,1-2H3,(H,28,29,31)(H2,30,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	297	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of Lck by HTRF kinase assay				J Med Chem 49: 5671-86 (2006) Article DOI: 10.1021/jm0605482 BindingDB Entry DOI: 10.7270/Q29G5MFD
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