Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50263515'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50263515 (2-(4-(6-(6-(2-(2-chloro-6-methylphenylamino)-1H-be...) Show SMILES Cc1nc(Nc2cc(ncn2)-n2c(Nc3c(C)cccc3Cl)nc3ccccc23)cc(n1)N1CCN(CCO)CC1 Show InChI InChI=1S/C29H31ClN10O/c1-19-6-5-7-21(30)28(19)37-29-35-22-8-3-4-9-23(22)40(29)26-16-24(31-18-32-26)36-25-17-27(34-20(2)33-25)39-12-10-38(11-13-39)14-15-41/h3-9,16-18,41H,10-15H2,1-2H3,(H,35,37)(H,31,32,33,34,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation (GNF) Curated by ChEMBL					Assay Description Inhibition of TEL fused Lck (unknown origin)-mediated proliferation of TEL-Lck transformed mouse BA/F3 cells after 48 hrs by bright-glo luciferase as...				Bioorg Med Chem Lett 18: 5618-21 (2008) Article DOI: 10.1016/j.bmcl.2008.08.104 BindingDB Entry DOI: 10.7270/Q2DN44WQ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50263515 (2-(4-(6-(6-(2-(2-chloro-6-methylphenylamino)-1H-be...) Show SMILES Cc1nc(Nc2cc(ncn2)-n2c(Nc3c(C)cccc3Cl)nc3ccccc23)cc(n1)N1CCN(CCO)CC1 Show InChI InChI=1S/C29H31ClN10O/c1-19-6-5-7-21(30)28(19)37-29-35-22-8-3-4-9-23(22)40(29)26-16-24(31-18-32-26)36-25-17-27(34-20(2)33-25)39-12-10-38(11-13-39)14-15-41/h3-9,16-18,41H,10-15H2,1-2H3,(H,35,37)(H,31,32,33,34,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation (GNF) Curated by ChEMBL					Assay Description Inhibition of TEL fused Lck-mediated proliferation of TEL-Lck transformed mouse BA/F3 cells after 48 hrs by bright-glo luciferase assay				Bioorg Med Chem Lett 18: 5618-21 (2008) Article DOI: 10.1016/j.bmcl.2008.08.104 BindingDB Entry DOI: 10.7270/Q2DN44WQ
					More data for this Ligand-Target Pair