Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50307880'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50307880 (CHEMBL598626 | N-(3-tert-butyl-1-phenyl-1H-pyrazol...) Show SMILES CC(C)(C)c1cc(NC(=O)c2cccc(Oc3cccc4[nH]c(=O)[nH]c34)c2)n(n1)-c1ccccc1 Show InChI InChI=1S/C27H25N5O3/c1-27(2,3)22-16-23(32(31-22)18-10-5-4-6-11-18)29-25(33)17-9-7-12-19(15-17)35-21-14-8-13-20-24(21)30-26(34)28-20/h4-16H,1-3H3,(H,29,33)(H2,28,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of LCK				J Med Chem 53: 1964-78 (2010) Article DOI: 10.1021/jm901509a BindingDB Entry DOI: 10.7270/Q2R211HN
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