Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50311891'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50311891 (3-(1-(6-(4-(diethylamino)butylamino)pyrimidin-4-yl...) Show SMILES CCN(CC)CCCCNc1cc(ncn1)-n1c(Nc2cc(ccc2C)C(=O)Nc2cccc(C)c2)nc2ccccc12 Show InChI InChI=1S/C34H40N8O/c1-5-41(6-2)19-10-9-18-35-31-22-32(37-23-36-31)42-30-15-8-7-14-28(30)39-34(42)40-29-21-26(17-16-25(29)4)33(43)38-27-13-11-12-24(3)20-27/h7-8,11-17,20-23H,5-6,9-10,18-19H2,1-4H3,(H,38,43)(H,39,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation (GNF) Curated by ChEMBL					Assay Description Inhibition of Tel-fused LCK expressed in mouse BAF3 cells				Bioorg Med Chem Lett 19: 6691-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.123 BindingDB Entry DOI: 10.7270/Q2Q52PRR
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50311891 (3-(1-(6-(4-(diethylamino)butylamino)pyrimidin-4-yl...) Show SMILES CCN(CC)CCCCNc1cc(ncn1)-n1c(Nc2cc(ccc2C)C(=O)Nc2cccc(C)c2)nc2ccccc12 Show InChI InChI=1S/C34H40N8O/c1-5-41(6-2)19-10-9-18-35-31-22-32(37-23-36-31)42-30-15-8-7-14-28(30)39-34(42)40-29-21-26(17-16-25(29)4)33(43)38-27-13-11-12-24(3)20-27/h7-8,11-17,20-23H,5-6,9-10,18-19H2,1-4H3,(H,38,43)(H,39,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	406	n/a	n/a	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation (GNF) Curated by ChEMBL					Assay Description Inhibition of Tel-fused LCK expressed in mouse BAF3 cells				Bioorg Med Chem Lett 19: 6691-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.123 BindingDB Entry DOI: 10.7270/Q2Q52PRR
					More data for this Ligand-Target Pair