Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50311944'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50311944 (CHEMBL1076466 | N-(3-(1-(6-(4-aminobutylamino)pyri...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1Nc1nc2ccccc2n1-c1cc(NCCCCN)ncn1 Show InChI InChI=1S/C30H29F3N8O/c1-19-11-12-22(38-28(42)20-7-6-8-21(15-20)30(31,32)33)16-24(19)40-29-39-23-9-2-3-10-25(23)41(29)27-17-26(36-18-37-27)35-14-5-4-13-34/h2-3,6-12,15-18H,4-5,13-14,34H2,1H3,(H,38,42)(H,39,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation (GNF) Curated by ChEMBL					Assay Description Inhibition of LCK				Bioorg Med Chem Lett 19: 6691-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.123 BindingDB Entry DOI: 10.7270/Q2Q52PRR
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50311944 (CHEMBL1076466 | N-(3-(1-(6-(4-aminobutylamino)pyri...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1Nc1nc2ccccc2n1-c1cc(NCCCCN)ncn1 Show InChI InChI=1S/C30H29F3N8O/c1-19-11-12-22(38-28(42)20-7-6-8-21(15-20)30(31,32)33)16-24(19)40-29-39-23-9-2-3-10-25(23)41(29)27-17-26(36-18-37-27)35-14-5-4-13-34/h2-3,6-12,15-18H,4-5,13-14,34H2,1H3,(H,38,42)(H,39,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	366	n/a	n/a	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation (GNF) Curated by ChEMBL					Assay Description Inhibition of Tel-fused LCK expressed in mouse BAF3 cells				Bioorg Med Chem Lett 19: 6691-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.123 BindingDB Entry DOI: 10.7270/Q2Q52PRR
					More data for this Ligand-Target Pair