Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50319571'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50319571 (CHEMBL1084451 | N-(4-(3-(2-((1-ethylpiperidin-4-yl...) Show SMILES CCN1CCC(CNc2nccc(n2)-c2cccnc2Oc2ccc(Nc3nc4ccccc4[nH]3)c3ccccc23)CC1 Show InChI InChI=1S/C34H34N8O/c1-2-42-20-16-23(17-21-42)22-37-33-36-19-15-28(38-33)26-10-7-18-35-32(26)43-31-14-13-27(24-8-3-4-9-25(24)31)39-34-40-29-11-5-6-12-30(29)41-34/h3-15,18-19,23H,2,16-17,20-22H2,1H3,(H,36,37,38)(H2,39,40,41)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	387	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of LCK				J Med Chem 53: 4502-10 (2010) Article DOI: 10.1021/jm100301x BindingDB Entry DOI: 10.7270/Q2T43T83
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