Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50372716'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50372716 (CHEMBL271018) Show SMILES CNc1ncc(C(=O)Nc2cc(ccc2C)C(=O)Nc2cccc(c2)C(F)(F)F)c(OC)n1 Show InChI InChI=1S/C22H20F3N5O3/c1-12-7-8-13(18(31)28-15-6-4-5-14(10-15)22(23,24)25)9-17(12)29-19(32)16-11-27-21(26-2)30-20(16)33-3/h4-11H,1-3H3,(H,28,31)(H,29,32)(H,26,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Lck by HTRF assay				Bioorg Med Chem Lett 18: 1172-6 (2008) Article DOI: 10.1016/j.bmcl.2007.11.123 BindingDB Entry DOI: 10.7270/Q2WD41FK
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