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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lyn' and Ligand = 'BDBM50255312'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Lyn


(Homo sapiens (Human))
BDBM50255312
PNG
(2-(5-((dimethylamino)methyl)-2-methoxyphenyl)-4-(4...)
Show SMILES COc1ccc(CN(C)C)cc1-c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N
Show InChI InChI=1S/C27H25N5OS/c1-16-19-9-10-29-23(19)7-6-22(16)31-26-18(13-28)14-30-27-21(26)12-25(34-27)20-11-17(15-32(2)3)5-8-24(20)33-4/h5-12,14,29H,15H2,1-4H3,(H,30,31)
PDB
MMDB

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PC cid
PC sid
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n/an/a 23n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of Lyn


Bioorg Med Chem Lett 19: 766-9 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.021
BindingDB Entry DOI: 10.7270/Q2KW5FX7
More data for this
Ligand-Target Pair