Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lyn' and Ligand = 'BDBM50311915'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lyn (Homo sapiens (Human))	BDBM50311915 (4-methyl-3-(1-(4-(3-(4-methylpiperazin-1-yl)propyl...) Show SMILES CN1CCN(CCCNc2ncnc(n2)-n2c(Nc3cc(ccc3C)C(=O)Nc3cccc(c3)C(F)(F)F)nc3ccccc23)CC1 Show InChI InChI=1S/C33H35F3N10O/c1-22-11-12-23(29(47)40-25-8-5-7-24(20-25)33(34,35)36)19-27(22)42-32-41-26-9-3-4-10-28(26)46(32)31-39-21-38-30(43-31)37-13-6-14-45-17-15-44(2)16-18-45/h3-5,7-12,19-21H,6,13-18H2,1-2H3,(H,40,47)(H,41,42)(H,37,38,39,43)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation (GNF) Curated by ChEMBL					Assay Description Inhibition of Tel-fused LYN expressed in mouse BAF3 cells				Bioorg Med Chem Lett 19: 6691-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.123 BindingDB Entry DOI: 10.7270/Q2Q52PRR
					More data for this Ligand-Target Pair