Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM50143216'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50143216 (CHEMBL3759079) Show SMILES Cn1cc(cn1)-c1cnc(Nc2cccc(Cn3nc(ccc3=O)-c3cnn(C)c3)c2)nc1 Show InChI InChI=1S/C23H21N9O/c1-30-14-18(11-26-30)17-9-24-23(25-10-17)28-20-5-3-4-16(8-20)13-32-22(33)7-6-21(29-32)19-12-27-31(2)15-19/h3-12,14-15H,13H2,1-2H3,(H,24,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human Mer using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA				Eur J Med Chem 108: 322-33 (2016) Article DOI: 10.1016/j.ejmech.2015.11.042 BindingDB Entry DOI: 10.7270/Q2DJ5HG7
					More data for this Ligand-Target Pair