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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM50444066'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM50444066
PNG
(CHEMBL3092799)
Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](N)CC2)n1)-c1ccccn1 |r,wU:11.10,wD:14.14,(15.98,-7.45,;17.32,-6.68,;18.65,-7.45,;19.98,-6.68,;21.32,-7.45,;22.65,-6.69,;23.98,-7.46,;25.32,-6.68,;25.32,-5.13,;23.98,-4.37,;23.98,-2.83,;22.64,-2.06,;21.31,-2.84,;19.98,-2.06,;19.98,-.52,;18.64,.26,;21.31,.25,;22.64,-.52,;22.65,-5.14,;26.65,-4.36,;27.98,-5.13,;29.31,-4.36,;29.3,-2.81,;27.96,-2.05,;26.64,-2.82,)|
Show InChI InChI=1S/C19H28N6/c1-2-3-11-22-19-23-13-16(17-6-4-5-12-21-17)18(25-19)24-15-9-7-14(20)8-10-15/h4-6,12-15H,2-3,7-11,20H2,1H3,(H2,22,23,24,25)/t14-,15-
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.80n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay


J Med Chem 56: 9683-92 (2014)


Article DOI: 10.1021/jm401387j
BindingDB Entry DOI: 10.7270/Q29W0GX8
More data for this
Ligand-Target Pair