Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM50444075'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444075 (CHEMBL3092790) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CN2CCC(F)(F)CC2)cn1 |r,wU:11.10,wD:14.14,(52.92,-33.3,;54.26,-32.53,;55.59,-33.3,;56.93,-32.54,;58.26,-33.31,;59.59,-32.54,;60.93,-33.31,;62.26,-32.54,;62.26,-30.99,;60.92,-30.22,;60.92,-28.68,;59.58,-27.92,;58.26,-28.69,;56.92,-27.91,;56.92,-26.37,;55.59,-25.6,;58.26,-25.6,;59.58,-26.37,;59.6,-30.99,;63.59,-30.21,;64.92,-30.98,;66.25,-30.21,;66.25,-28.67,;67.58,-27.89,;68.91,-28.65,;68.91,-30.19,;70.24,-30.96,;71.58,-30.19,;72.35,-31.52,;73.12,-30.18,;71.57,-28.64,;70.23,-27.87,;64.9,-27.9,;63.58,-28.68,)| Show InChI InChI=1S/C25H36F2N6O/c1-2-3-12-28-24-30-16-21(23(32-24)31-19-5-7-20(34)8-6-19)22-9-4-18(15-29-22)17-33-13-10-25(26,27)11-14-33/h4,9,15-16,19-20,34H,2-3,5-8,10-14,17H2,1H3,(H2,28,30,31,32)/t19-,20-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair