Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM140314'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM140314 (US8912173, 40) Show SMILES NC(=O)c1cccnc1COc1cc(cc2ncccc12)-c1ccc(CN2CCOCC2)cc1 Show InChI InChI=1S/C27H26N4O3/c28-27(32)23-4-2-10-30-25(23)18-34-26-16-21(15-24-22(26)3-1-9-29-24)20-7-5-19(6-8-20)17-31-11-13-33-14-12-31/h1-10,15-16H,11-14,17-18H2,(H2,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.5	-80
Boehringer Ingelheim International GmbH US Patent					Assay Description Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...				US Patent US8912173 (2014) BindingDB Entry DOI: 10.7270/Q2TX3D3T
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM140314 (US8912173, 40) Show SMILES NC(=O)c1cccnc1COc1cc(cc2ncccc12)-c1ccc(CN2CCOCC2)cc1 Show InChI InChI=1S/C27H26N4O3/c28-27(32)23-4-2-10-30-25(23)18-34-26-16-21(15-24-22(26)3-1-9-29-24)20-7-5-19(6-8-20)17-31-11-13-33-14-12-31/h1-10,15-16H,11-14,17-18H2,(H2,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.40	n/a	n/a	n/a	n/a	7.5	-80
Boehringer Ingelheim International GmbH US Patent					Assay Description Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...				US Patent US8912173 (2014) BindingDB Entry DOI: 10.7270/Q2TX3D3T
					More data for this Ligand-Target Pair