Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM144566'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM144566 (US8969568, 119) Show SMILES CC(C)Oc1ccc(cc1)-c1cc2ncccc2c(OC[C@H]2CNC(=O)C2)n1 |r| Show InChI InChI=1S/C22H23N3O3/c1-14(2)28-17-7-5-16(6-8-17)19-11-20-18(4-3-9-23-20)22(25-19)27-13-15-10-21(26)24-12-15/h3-9,11,14-15H,10,12-13H2,1-2H3,(H,24,26)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH & Co. KG US Patent					Assay Description Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...				US Patent US8969568 (2015) BindingDB Entry DOI: 10.7270/Q2154FRD
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