Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM172901'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM172901 (US9096579, 3) Show SMILES CN1CCN(CC1)C(=O)c1cc2cc(Nc3nccc(n3)-c3cn(C)cn3)cc(Cl)c2[nH]1 Show InChI InChI=1S/C22H23ClN8O/c1-29-5-7-31(8-6-29)21(32)18-10-14-9-15(11-16(23)20(14)27-18)26-22-24-4-3-17(28-22)19-12-30(2)13-25-19/h3-4,9-13,27H,5-8H2,1-2H3,(H,24,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...				US Patent US9096579 (2015) BindingDB Entry DOI: 10.7270/Q2F76B9H
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM172901 (US9096579, 3) Show SMILES CN1CCN(CC1)C(=O)c1cc2cc(Nc3nccc(n3)-c3cn(C)cn3)cc(Cl)c2[nH]1 Show InChI InChI=1S/C22H23ClN8O/c1-29-5-7-31(8-6-29)21(32)18-10-14-9-15(11-16(23)20(14)27-18)26-22-24-4-3-17(28-22)19-12-30(2)13-25-19/h3-4,9-13,27H,5-8H2,1-2H3,(H,24,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...				US Patent US9096579 (2015) BindingDB Entry DOI: 10.7270/Q2F76B9H
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM172901 (US9096579, 3) Show SMILES CN1CCN(CC1)C(=O)c1cc2cc(Nc3nccc(n3)-c3cn(C)cn3)cc(Cl)c2[nH]1 Show InChI InChI=1S/C22H23ClN8O/c1-29-5-7-31(8-6-29)21(32)18-10-14-9-15(11-16(23)20(14)27-18)26-22-24-4-3-17(28-22)19-12-30(2)13-25-19/h3-4,9-13,27H,5-8H2,1-2H3,(H,24,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11.4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...				US Patent US9096579 (2015) BindingDB Entry DOI: 10.7270/Q2F76B9H
					More data for this Ligand-Target Pair