Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM173069'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM173069 (US9096579, 171) Show SMILES Cc1noc(n1)-c1cc2cc(Nc3nccc(n3)-c3cn(C)cn3)cc(C)c2[nH]1 Show InChI InChI=1S/C20H18N8O/c1-11-6-14(7-13-8-16(25-18(11)13)19-23-12(2)27-29-19)24-20-21-5-4-15(26-20)17-9-28(3)10-22-17/h4-10,25H,1-3H3,(H,21,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...				US Patent US9096579 (2015) BindingDB Entry DOI: 10.7270/Q2F76B9H
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM173069 (US9096579, 171) Show SMILES Cc1noc(n1)-c1cc2cc(Nc3nccc(n3)-c3cn(C)cn3)cc(C)c2[nH]1 Show InChI InChI=1S/C20H18N8O/c1-11-6-14(7-13-8-16(25-18(11)13)19-23-12(2)27-29-19)24-20-21-5-4-15(26-20)17-9-28(3)10-22-17/h4-10,25H,1-3H3,(H,21,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...				US Patent US9096579 (2015) BindingDB Entry DOI: 10.7270/Q2F76B9H
					More data for this Ligand-Target Pair