Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM182767'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM182767 (US9145414, 17 | US9145414, 9) Show SMILES CCn1ccc2c(Nc3nc(N[C@@H]4CCCC[C@@H]4N)nnc3C(N)=O)cccc12 |r| Show InChI InChI=1S/C20H26N8O/c1-2-28-11-10-12-14(8-5-9-16(12)28)23-19-17(18(22)29)26-27-20(25-19)24-15-7-4-3-6-13(15)21/h5,8-11,13,15H,2-4,6-7,21H2,1H3,(H2,22,29)(H2,23,24,25,27)/t13-,15+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.210	n/a	n/a	n/a	n/a	7.5	25
TAIHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...				US Patent US9145414 (2015) BindingDB Entry DOI: 10.7270/Q2513X18
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM182767 (US9145414, 17 | US9145414, 9) Show SMILES CCn1ccc2c(Nc3nc(N[C@@H]4CCCC[C@@H]4N)nnc3C(N)=O)cccc12 |r| Show InChI InChI=1S/C20H26N8O/c1-2-28-11-10-12-14(8-5-9-16(12)28)23-19-17(18(22)29)26-27-20(25-19)24-15-7-4-3-6-13(15)21/h5,8-11,13,15H,2-4,6-7,21H2,1H3,(H2,22,29)(H2,23,24,25,27)/t13-,15+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	7.4	25
TAIHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The in vitro inhibitory activity of the compound against Aurora B kinase activity was assayed with reference to a method described in patent public...				US Patent US9145414 (2015) BindingDB Entry DOI: 10.7270/Q2513X18
					More data for this Ligand-Target Pair