Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM205262'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM205262 (US9249125, 15) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5[nH]ncc5c4)n3)c3ccccc23)n(n1)-c1ccc(OCCN2CCOCC2)nc1 Show InChI InChI=1S/C40H41N11O4/c1-40(2,3)34-23-35(51(49-34)28-9-13-36(42-25-28)54-21-18-50-16-19-53-20-17-50)46-39(52)45-32-11-12-33(30-7-5-4-6-29(30)32)55-37-14-15-41-38(47-37)44-27-8-10-31-26(22-27)24-43-48-31/h4-15,22-25H,16-21H2,1-3H3,(H,43,48)(H,41,44,47)(H2,45,46,52)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
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