Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM243351'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM243351 (4-{5-[3-(4-Ethyl- pyrimidin-2-ylamino)- phenyl]-ox...) Show SMILES CCc1ccnc(Nc2cccc(c2)-c2cnc(o2)N2CCNC(=O)C22CC2)n1 Show InChI InChI=1S/C21H22N6O2/c1-2-15-6-9-23-19(25-15)26-16-5-3-4-14(12-16)17-13-24-20(29-17)27-11-10-22-18(28)21(27)7-8-21/h3-6,9,12-13H,2,7-8,10-11H2,1H3,(H,22,28)(H,23,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	7.8	25
AB SCIENCE US Patent					Assay Description SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...				US Patent US10053455 (2018) BindingDB Entry DOI: 10.7270/Q27946PV
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