Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM243357'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM243357 (4-{5-[3-(4-Isopropyl- pyrimidin-2-ylamino)- phenyl...) Show SMILES CC(C)c1ccnc(Nc2cccc(c2)-c2cnc(o2)N2CCNC(=O)C22CC2)n1 Show InChI InChI=1S/C22H24N6O2/c1-14(2)17-6-9-24-20(27-17)26-16-5-3-4-15(12-16)18-13-25-21(30-18)28-11-10-23-19(29)22(28)7-8-22/h3-6,9,12-14H,7-8,10-11H2,1-2H3,(H,23,29)(H,24,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	7.8	25
AB SCIENCE US Patent					Assay Description SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...				US Patent US10053455 (2018) BindingDB Entry DOI: 10.7270/Q27946PV
					More data for this Ligand-Target Pair