Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM290677'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM290677 (4-(3-(1H-tetrazol-1-yl)phenylamino)-2-((1R,2S)-2-a...) Show SMILES N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2cccc(c2)-n2cnnn2)n1 |r| Show InChI InChI=1S/C18H22N10O/c19-14-6-1-2-7-15(14)24-18-21-9-13(16(20)29)17(25-18)23-11-4-3-5-12(8-11)28-10-22-26-27-28/h3-5,8-10,14-15H,1-2,6-7,19H2,(H2,20,29)(H2,21,23,24,25)/t14-,15+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	7.5	25
Portola Pharmaceuticals, Inc. US Patent					Assay Description Potency of candidate molecules for inhibiting syk tyrosine phosphorylation activity is assessed by measuring the ability of a test compound to inhibi...				US Patent US9579320 (2017) BindingDB Entry DOI: 10.7270/Q2K07692
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