Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM291025'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM291025 ((S)-2-(2-aminobutylamino)-4-(1-ethyl-1H-indol-4-yl...) Show SMILES CC[C@H](N)CNc1ncc(C(N)=O)c(Nc2cccc3n(CC)ccc23)n1 |r| Show InChI InChI=1S/C19H25N7O/c1-3-12(20)10-22-19-23-11-14(17(21)27)18(25-19)24-15-6-5-7-16-13(15)8-9-26(16)4-2/h5-9,11-12H,3-4,10,20H2,1-2H3,(H2,21,27)(H2,22,23,24,25)/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	7.5	25
Portola Pharmaceuticals, Inc. US Patent					Assay Description Potency of candidate molecules for inhibiting syk tyrosine phosphorylation activity is assessed by measuring the ability of a test compound to inhibi...				US Patent US9579320 (2017) BindingDB Entry DOI: 10.7270/Q2K07692
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