Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM50076192'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50076192 (CHEMBL3416021) Show SMILES N[C@H]1CCCC[C@H]1Nc1ccc(C(N)=O)c(Nc2cccc(c2)-n2nccn2)n1 |r| Show InChI InChI=1S/C20H24N8O/c21-16-6-1-2-7-17(16)26-18-9-8-15(19(22)29)20(27-18)25-13-4-3-5-14(12-13)28-23-10-11-24-28/h3-5,8-12,16-17H,1-2,6-7,21H2,(H2,22,29)(H2,25,26,27)/t16-,17+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of Syk (unknown origin) using 5-Fluo-Ahx-GAPDYENLQELNKK-Amide as substrate after 60 mins by microfluidic mobility shift assay				J Med Chem 58: 1950-63 (2015) Article DOI: 10.1021/jm5018863 BindingDB Entry DOI: 10.7270/Q2G44S0C
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50076192 (CHEMBL3416021) Show SMILES N[C@H]1CCCC[C@H]1Nc1ccc(C(N)=O)c(Nc2cccc(c2)-n2nccn2)n1 |r| Show InChI InChI=1S/C20H24N8O/c21-16-6-1-2-7-17(16)26-18-9-8-15(19(22)29)20(27-18)25-13-4-3-5-14(12-13)28-23-10-11-24-28/h3-5,8-12,16-17H,1-2,6-7,21H2,(H2,22,29)(H2,25,26,27)/t16-,17+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	445	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of Syk in anti-igM stimulated human Ramos B cells assessed as phospho-BLNK level preincubated for 30 mins followed by anti-IgM stimulation...				J Med Chem 58: 1950-63 (2015) Article DOI: 10.1021/jm5018863 BindingDB Entry DOI: 10.7270/Q2G44S0C
					More data for this Ligand-Target Pair