Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM50123584'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50123584 (CHEMBL3622205) Show SMILES [H][C@@]1(CNC(=O)C1)[C@@H](C)Oc1nc(cc2ncsc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C16H17N5O2S/c1-9(10-3-14(22)17-5-10)23-16-15-13(18-8-24-15)4-12(20-16)11-6-19-21(2)7-11/h4,6-10H,3,5H2,1-2H3,(H,17,22)/t9-,10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of Syk (unknown origin) using 5-Fluo-Ahx-GAPDYENLQELNKK-Amide as substrate after 60 mins by microfluidic mobility shift assay				Bioorg Med Chem Lett 25: 4642-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.037 BindingDB Entry DOI: 10.7270/Q2XD13HG
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50123584 (CHEMBL3622205) Show SMILES [H][C@@]1(CNC(=O)C1)[C@@H](C)Oc1nc(cc2ncsc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C16H17N5O2S/c1-9(10-3-14(22)17-5-10)23-16-15-13(18-8-24-15)4-12(20-16)11-6-19-21(2)7-11/h4,6-10H,3,5H2,1-2H3,(H,17,22)/t9-,10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	284	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of Syk in anti-igM stimulated human Ramos B cells assessed as phospho-BLNK level preincubated for 30 mins followed by anti-IgM stimulation...				Bioorg Med Chem Lett 25: 4642-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.037 BindingDB Entry DOI: 10.7270/Q2XD13HG
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50123584 (CHEMBL3622205) Show SMILES [H][C@@]1(CNC(=O)C1)[C@@H](C)Oc1nc(cc2ncsc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C16H17N5O2S/c1-9(10-3-14(22)17-5-10)23-16-15-13(18-8-24-15)4-12(20-16)11-6-19-21(2)7-11/h4,6-10H,3,5H2,1-2H3,(H,17,22)/t9-,10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	538	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of Syk in anti-CD32 stimulated CD14+ human monocytes in presence of 90% human blood assessed as phospho-SLP76 level preincubated for 30 mi...				Bioorg Med Chem Lett 25: 4642-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.037 BindingDB Entry DOI: 10.7270/Q2XD13HG
					More data for this Ligand-Target Pair