Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM50126400'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50126400 (CHEMBL30873 | N*1*-[7-(4-Isopropyl-phenyl)-[1,6]na...) Show SMILES CC(C)c1ccc(cc1)-c1cc2ncccc2c(NCCCN)n1 Show InChI InChI=1S/C20H24N4/c1-14(2)15-6-8-16(9-7-15)18-13-19-17(5-3-11-22-19)20(24-18)23-12-4-10-21/h3,5-9,11,13-14H,4,10,12,21H2,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against spleen tyrosine kinase (SYK)				Bioorg Med Chem Lett 13: 1415-8 (2003) BindingDB Entry DOI: 10.7270/Q2MC8ZCJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50126400 (CHEMBL30873 | N*1*-[7-(4-Isopropyl-phenyl)-[1,6]na...) Show SMILES CC(C)c1ccc(cc1)-c1cc2ncccc2c(NCCCN)n1 Show InChI InChI=1S/C20H24N4/c1-14(2)15-6-8-16(9-7-15)18-13-19-17(5-3-11-22-19)20(24-18)23-12-4-10-21/h3,5-9,11,13-14H,4,10,12,21H2,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Rigel, Inc. Curated by ChEMBL					Assay Description Inhibition of SYK				J Med Chem 55: 3614-43 (2012) Article DOI: 10.1021/jm201271b BindingDB Entry DOI: 10.7270/Q2NZ88RC
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50126400 (CHEMBL30873 | N*1*-[7-(4-Isopropyl-phenyl)-[1,6]na...) Show SMILES CC(C)c1ccc(cc1)-c1cc2ncccc2c(NCCCN)n1 Show InChI InChI=1S/C20H24N4/c1-14(2)15-6-8-16(9-7-15)18-13-19-17(5-3-11-22-19)20(24-18)23-12-4-10-21/h3,5-9,11,13-14H,4,10,12,21H2,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant Syk (unknown origin)				Bioorg Med Chem Lett 19: 1944-9 (2009) Article DOI: 10.1016/j.bmcl.2009.02.049 BindingDB Entry DOI: 10.7270/Q2WM1D98
					More data for this Ligand-Target Pair