Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM50126403'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50126403 (CHEMBL33009 | N*1*-(7-{4-[(3-Dimethylamino-propyl)...) Show SMILES CN(C)CCCN(C)c1ccc(cc1)-c1cc2ncccc2c(NCCCN)n1 Show InChI InChI=1S/C23H32N6/c1-28(2)15-6-16-29(3)19-10-8-18(9-11-19)21-17-22-20(7-4-13-25-22)23(27-21)26-14-5-12-24/h4,7-11,13,17H,5-6,12,14-16,24H2,1-3H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against spleen tyrosine kinase (SYK)				Bioorg Med Chem Lett 13: 1415-8 (2003) BindingDB Entry DOI: 10.7270/Q2MC8ZCJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50126403 (CHEMBL33009 | N*1*-(7-{4-[(3-Dimethylamino-propyl)...) Show SMILES CN(C)CCCN(C)c1ccc(cc1)-c1cc2ncccc2c(NCCCN)n1 Show InChI InChI=1S/C23H32N6/c1-28(2)15-6-16-29(3)19-10-8-18(9-11-19)21-17-22-20(7-4-13-25-22)23(27-21)26-14-5-12-24/h4,7-11,13,17H,5-6,12,14-16,24H2,1-3H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Punjabi University Curated by ChEMBL					Assay Description Inhibition of spleen tyrosine kinase (unknown origin)				Eur J Med Chem 67: 434-46 (2013) Article DOI: 10.1016/j.ejmech.2013.04.070 BindingDB Entry DOI: 10.7270/Q2Z039JB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50126403 (CHEMBL33009 | N*1*-(7-{4-[(3-Dimethylamino-propyl)...) Show SMILES CN(C)CCCN(C)c1ccc(cc1)-c1cc2ncccc2c(NCCCN)n1 Show InChI InChI=1S/C23H32N6/c1-28(2)15-6-16-29(3)19-10-8-18(9-11-19)21-17-22-20(7-4-13-25-22)23(27-21)26-14-5-12-24/h4,7-11,13,17H,5-6,12,14-16,24H2,1-3H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Rigel, Inc. Curated by ChEMBL					Assay Description Inhibition of SYK				J Med Chem 55: 3614-43 (2012) Article DOI: 10.1021/jm201271b BindingDB Entry DOI: 10.7270/Q2NZ88RC
					More data for this Ligand-Target Pair