Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM50126428'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50126428 (1-Amino-3-[7-(4-dimethylamino-phenyl)-[1,6]naphthy...) Show SMILES CN(C)c1ccc(cc1)-c1cc2ncccc2c(NCC(O)CN)n1 Show InChI InChI=1S/C19H23N5O/c1-24(2)14-7-5-13(6-8-14)17-10-18-16(4-3-9-21-18)19(23-17)22-12-15(25)11-20/h3-10,15,25H,11-12,20H2,1-2H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant Syk (unknown origin)				Bioorg Med Chem Lett 19: 1944-9 (2009) Article DOI: 10.1016/j.bmcl.2009.02.049 BindingDB Entry DOI: 10.7270/Q2WM1D98
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50126428 (1-Amino-3-[7-(4-dimethylamino-phenyl)-[1,6]naphthy...) Show SMILES CN(C)c1ccc(cc1)-c1cc2ncccc2c(NCC(O)CN)n1 Show InChI InChI=1S/C19H23N5O/c1-24(2)14-7-5-13(6-8-14)17-10-18-16(4-3-9-21-18)19(23-17)22-12-15(25)11-20/h3-10,15,25H,11-12,20H2,1-2H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against spleen tyrosine kinase (SYK)				Bioorg Med Chem Lett 13: 1415-8 (2003) BindingDB Entry DOI: 10.7270/Q2MC8ZCJ
					More data for this Ligand-Target Pair