Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM50132456'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50132456 (3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-y...) Show SMILES CCNS(=O)(=O)c1ccc2NC(=O)\C(=C/c3cn(C)c4ccc(OC)cc34)c2c1 Show InChI InChI=1S/C21H21N3O4S/c1-4-22-29(26,27)15-6-7-19-17(11-15)18(21(25)23-19)9-13-12-24(2)20-8-5-14(28-3)10-16(13)20/h5-12,22H,4H2,1-3H3,(H,23,25)/b18-9-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactis				Bioorg Med Chem Lett 13: 3111-4 (2003) BindingDB Entry DOI: 10.7270/Q2ZG6SS7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50132456 (3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-y...) Show SMILES CCNS(=O)(=O)c1ccc2NC(=O)\C(=C/c3cn(C)c4ccc(OC)cc34)c2c1 Show InChI InChI=1S/C21H21N3O4S/c1-4-22-29(26,27)15-6-7-19-17(11-15)18(21(25)23-19)9-13-12-24(2)20-8-5-14(28-3)10-16(13)20/h5-12,22H,4H2,1-3H3,(H,23,25)/b18-9-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant Syk (unknown origin)				Bioorg Med Chem Lett 19: 1944-9 (2009) Article DOI: 10.1016/j.bmcl.2009.02.049 BindingDB Entry DOI: 10.7270/Q2WM1D98
					More data for this Ligand-Target Pair