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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM50249226'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM50249226
PNG
(CHEMBL513985 | N-(3-phenoxyphenyl)-4-(thiazol-2-yl...)
Show SMILES N(c1cccc(Oc2ccccc2)c1)c1nccc(n1)-c1nccs1
Show InChI InChI=1S/C19H14N4OS/c1-2-6-15(7-3-1)24-16-8-4-5-14(13-16)22-19-21-10-9-17(23-19)18-20-11-12-25-18/h1-13H,(H,21,22,23)
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Article
PubMed
630n/an/an/an/an/an/an/an/a



Vertex Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of SYK (unknown origin)


Bioorg Med Chem Lett 18: 6231-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.09.106
BindingDB Entry DOI: 10.7270/Q25Q4VZT
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM50249226
PNG
(CHEMBL513985 | N-(3-phenoxyphenyl)-4-(thiazol-2-yl...)
Show SMILES N(c1cccc(Oc2ccccc2)c1)c1nccc(n1)-c1nccs1
Show InChI InChI=1S/C19H14N4OS/c1-2-6-15(7-3-1)24-16-8-4-5-14(13-16)22-19-21-10-9-17(23-19)18-20-11-12-25-18/h1-13H,(H,21,22,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant Syk (unknown origin)


Bioorg Med Chem Lett 19: 1944-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.049
BindingDB Entry DOI: 10.7270/Q2WM1D98
More data for this
Ligand-Target Pair