Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM50274757'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50274757 (5-((1S,2R)-2-Aminocyclohexylamino)-7-(3,5-dimethox...) Show SMILES COc1cc(Nc2nc(N[C@H]3CCCC[C@H]3N)n3cc(nc3c2C(N)=O)-c2ccccc2)cc(OC)c1 |r| Show InChI InChI=1S/C27H31N7O3/c1-36-18-12-17(13-19(14-18)37-2)30-25-23(24(29)35)26-31-22(16-8-4-3-5-9-16)15-34(26)27(33-25)32-21-11-7-6-10-20(21)28/h3-5,8-9,12-15,20-21,30H,6-7,10-11,28H2,1-2H3,(H2,29,35)(H,32,33)/t20-,21+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Inhibition of human Syk expressed in Sf9 cells				Bioorg Med Chem 16: 9247-60 (2008) Article DOI: 10.1016/j.bmc.2008.09.015 BindingDB Entry DOI: 10.7270/Q2GM887N
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