Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM50396074'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50396074 (CHEMBL2170585) Show SMILES COc1ccc(cc1OC)-c1cc2nccn2c(Nc2ccc3cn[nH]c3c2)n1 Show InChI InChI=1S/C21H18N6O2/c1-28-18-6-4-13(9-19(18)29-2)16-11-20-22-7-8-27(20)21(25-16)24-15-5-3-14-12-23-26-17(14)10-15/h3-12H,1-2H3,(H,23,26)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rigel, Inc. Curated by ChEMBL					Assay Description Inhibition of SYK				J Med Chem 55: 3614-43 (2012) Article DOI: 10.1021/jm201271b BindingDB Entry DOI: 10.7270/Q2NZ88RC
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50396074 (CHEMBL2170585) Show SMILES COc1ccc(cc1OC)-c1cc2nccn2c(Nc2ccc3cn[nH]c3c2)n1 Show InChI InChI=1S/C21H18N6O2/c1-28-18-6-4-13(9-19(18)29-2)16-11-20-22-7-8-27(20)21(25-16)24-15-5-3-14-12-23-26-17(14)10-15/h3-12H,1-2H3,(H,23,26)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a
Rigel, Inc. Curated by ChEMBL					Assay Description Inhibition of SYK assessed as IL4 production by cell based assay				J Med Chem 55: 3614-43 (2012) Article DOI: 10.1021/jm201271b BindingDB Entry DOI: 10.7270/Q2NZ88RC
					More data for this Ligand-Target Pair