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Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase receptor TYRO3' and Ligand = 'BDBM50425869'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))		BDBM50425869
PNG
(CHEMBL2312653)
Show SMILES Cc1cc(on1)-c1cnc(Nc2cc(Cl)cc(Cl)c2)nc1NC1CCNCC1
Show InChI InChI=1S/C19H20Cl2N6O/c1-11-6-17(28-27-11)16-10-23-19(25-15-8-12(20)7-13(21)9-15)26-18(16)24-14-2-4-22-5-3-14/h6-10,14,22H,2-5H2,1H3,(H2,23,24,25,26)
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MMDB

KEGG

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Similars
Article
PubMed
n/an/a 92n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of Sky (unknown origin) by ELISA kinase assay in presence of 60 uM ATP

Bioorg Med Chem Lett 23: 1051-5 (2013)


Article DOI: 10.1016/j.bmcl.2012.12.028
BindingDB Entry DOI: 10.7270/Q2XW4M38
More data for this
Ligand-Target Pair